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Care from nature: what can CBC offer you?

Dropper bottle filled with oil enriched with the cannabinoid CBC (cannabichromene)

CBC is a long-discovered but little-known cannabinoid that is only now gaining more attention due to the growing interest in alternative means of promoting a healthy lifestyle. Let's find out what the origins of this compound are and how its potential effects can benefit you too!

What is the CBC?

CBC, or cannabichromene, is a non-psychoactive cannabinoid found in cannabis. It is one of the four most abundant cannabinoids in the plant.

Scientists Raphael Mechoulam and Yehiel Gaoni discovered it at the Hebrew University of Jerusalem in 1966. However, it was not until two decades later that we gained the first knowledge of its potential effects. And it is only today that research is giving us more detailed information about how CBC actually works.

Although our knowledge of this cannabinoid is limited compared to, for example, CBD or THC, scientific studies suggest that it could improve digestion, reduce inflammation, bring mental well-being and regenerate the brain.

How does the CBC come into being?

The origin of CBC is cannabigerol acid (CBGA). This is converted to cannabichromenic acid (CBCA) through an enzymatic process. CBC from CBGA is formed by decarboxylation, a process in which the carboxyl group is heated and removed.

CBC from a chemistry perspective

The molecular formula of CBC is C21H30O2. It contains 21 carbon atoms, 30 hydrogen atoms and 2 oxygen atoms.

 

The molecular formula of CBC is C₂₁H₃₀O₂ and has one hydroxyl group (-OH)

CBC has a bicyclic structure, which means that the molecule consists of two connected rings. This is a more complex structure than, for example, the popular CBD, which is monocyclic. Therefore, CBC does not primarily bind to the same receptors in the endocannabinoid system as CBD, but in particular to TRP receptors. These receptors play a key role in a wide variety of biological functions, such as pain perception or inflammation.

CBC has only one hydroxyl group (-OH) and is therefore less polar than, for example, CBD, which has two hydroxyl groups. This means less variation in the distribution of the electrical charge in the molecule. CBC is therefore less soluble in water but more soluble in fats. Because cell membranes are made up of non-polar lipids (fats), CBC penetrates them more easily, ensuring faster absorption. Due to its lower polarity, CBC is chemically more stable and resistant to external influences, which slows down degradation

Effects of CBC

Research to date suggests that CBC has the potential to become a valuable natural aid for both health and mental balance.

Better digestion

The unique property of cannabichromene is its ability to harmonize the activity of the digestive tract without side effects. It can regulate excessive intestinal motility, thus improving nutrient absorption and relieving unpleasant digestive discomforts such as cramps or diarrhoea.

CBC could be key to the treatment of a number of digestive tract diseases, such as Crohn's disease or irritable bowel syndrome. Cannabichromene could also relieve digestive problems associated with various food intolerances.

Fighting inflammation

In previous studies, CBC has shown significant anti-inflammatory effects. Research has shown that cannabichromene even performed better than phenylbutazone, a commonly used anti-inflammatory drug. CBC showed strong antibacterial activity and mild antifungal properties. Thus, CBC appears to have the potential to be an effective agent in the treatment of inflammation, bacterial infections and some fungal diseases.

Effect on psychological well-being

Like the more well-known CBD, CBC has a positive effect on psychological well-being. Research has shown that CBC has antidepressant effects at lower doses and calms and lowers body temperature at higher doses.

Importantly, it does not cause muscle stiffness, a common side effect typical of many other substances used to promote mental health. CBC could thus be an interesting alternative to conventional antipsychotics, benzodiazepines and other sedatives and opiates.

Supporting brain regeneration

A 2013 study shows that CBCs increase the viability of neural stem and progenitor cells during differentiation, the process by which immature cells are transformed into specialized cells with specific functions. In addition, it prevents cells from turning into astrocytes, which could inhibit brain regeneration.

These properties suggest its benefits for brain health and its potential use in regenerative medicine, for example in the restoration of neurons after brain injury or in the prevention and treatment of neurodegenerative diseases such as Alzheimer's or Parkinson's disease.

 

Properties of CBC suggest benefits for brain health and potential use in regenerative medicine

When cannabinoids are in harmony

In the endocannabinoid system, individual compounds from cannabis have specific roles that can complement and reinforce each other when working together. This phenomenon is called the synergistic effect or the entourage effect.

The four main cannabinoids in cannabis are CBC, CBD, CBG and THC. The cannabinoids CBC, CBD and CBG are non-psychoactive and have antidepressant properties. THC is psychoactive and has strong analgesic effects that can help manage chronic pain.

CBC aids in better digestion, CBD can support immunity and metabolism, and CBG positively affects urinary tract health.

In addition to cannabinoids, other substances from cannabis - terpenes and flavonoids - also act in the endocannabinoid system. The combination of these substances can lead to a positive complex effect on human health.

CBC products

CBC is not yet a standard part of the offer of e-shops with cannabis products. However, given its unique properties and ongoing research, it is expected that the CBC offer will soon expand.

Here you can find isolate 10% CBC oil. The oil is easy to dose, quickly absorbed and can be added to drinks, food or dripped under the tongue for faster onset of effects.

We also offer vape pen and cartridges containing CBC, CBG, basil, cinnamon and chamomile.

 

Hemnia Products, CBC vape pen and cartridge, CBC oil

CBC is often part of other broad-spectrum and full-spectrum products.

Conclusion

CBC, cannabichromene, is one of the four most abundant cannabinoids in cannabis, but although its existence has been known for decades, its therapeutic potential has only recently been discovered by scientists.

CBC is non-psychoactive and excels in its ability to harmonize digestion, fight inflammation, bacteria and fungi, while promoting brain health and mental well-being.

CBC can provide complex health benefits when combined with other cannabinoids such as CBD. While the supply of CBC products is still limited, we expect to see wider use and improved availability as awareness of the effects of this cannabinoid grows.

  

Author: Natálie Kubíčková

 

Foto: AI

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