A new level of relaxation: The natural cannabinoid CBDP with relaxing effects

07. 04. 2025

If you're interested in the world of cannabinoids, you've probably heard of CBD, CBG or CBN. But scientists have discovered another compound - CBDP (cannabidiophorol). What exactly is CBDP, what effects does it hide and what do we know about it so far? Is it more potent than CBD? Let's take a closer look at this phytocannabinoid 🔎.

• What is CBDP?
• Structure of CBDP vs. CBD
• How is commercially available CBDP produced?
• Effects of CBDP
• Side effects
• CBDP products
• Hemnia premium CBDP and CBN vape and Deep Relaxation cartridges
• Conclusion

What is CBDP?

Cannabidiophorol (CBDP) is a rare phytocannabinoid that occurs naturally in cannabis, but only in very small amounts 🌿. It is a heptyl homologue of cannabidiol (CBD) - it belongs to the same group of chemical compounds, so it shares similar structure and properties with CBD.

Until 2019, the cannabinoid CBDP was referred to as a synthetic compound and can also be found under the names CBD-C7 and CBD-heptyl.

In 2019, a team of Italian scientists identified it as a natural cannabinoid, and at the same time, they also managed to discover the cannabinoid THCP. Both of these compounds have been found in different varieties of medicinal cannabis.

Behind these breakthroughs are advanced analytical technologies, notably high-performance liquid chromatography (HPLC) and high-resolution mass spectrometry (HRMS), which make it possible to identify even very rare cannabinoids.

Structure of CBDP vs. CBD

The main difference between CBDP and CBD is that CBD has a 5-member alkyl chain, whereas CBDP has a longer, 7-member side chain, which may affect its biological activity and interaction with receptors of the endocannabinoid system.

The molecular formula of CBDP is C23H34O2 (23 carbon atoms, 34 hydrogen atoms, 2 oxygen atoms). CBD has the formula C21H30O2 (21 carbon atoms, 30 hydrogen atoms, 2 oxygen atoms). 

 

How is commercially available CBDP produced?

CBDP is naturally found in cannabis, but only in very low concentrations, so it is synthesised for commercial use from a CBD isolate and labeled a semi-synthetic cannabinoid.

The process used to produce it is called isomerisation, in which a molecule, ion or fragment of a CBD molecule is transformed into an isomer with a different structure.

CBD isolate 💎, from which CBDP is produced, is the purest form of cannabidiol with a CBD content of 96 to 100 %, with zero THC.  In some cases, terpenes and terpenoids may be present in the isolate in smaller amounts, which affect taste, aroma and potency.

Effects of CBDP

Since CBDP is still an understudied cannabinoid, there are many questions surrounding it 💭. Let's take a look at the information we have so far on its effects:

• The structure of CBDP suggests that it could have different or possibly stronger effects than CBD.

• According to a 2018 study, cannabinoids with a longer side chain are thought to have a higher affinity for CB1 and CB2 receptors.

• In contrast, a 2019 study from an Italian team suggested that CBDP has low affinity for both CB1 and CB2 receptors.

• The results of the 2024 study (the first publication to examine the receptor activity of CBDP in vitro) confirmed that CBDP has low affinity for CB1 and CB2 receptors, as does CBD. This means that CBDP is unlikely to act directly on the major cannabinoid receptors. Researchers believe that CBDP could act on other receptors in the body, such as TRP receptors or serotonin receptors (5-HT1A), similar to CBD.

• There are theoretical implications for neuroprotective, anti-inflammatory and analgesic properties, but direct studies are lacking.

• A 2021 study from investigated the potential effects of CBDP against breast cancer, and suggested that CBDP acts similarly to CBD, but may be more effective. The results suggest that CBDP could play a role in the fight against cancer cells, while also appearing to increase the effectiveness of some anti-cancer drugs already in use. When CBDP was administered together with CBD, it enhanced each of these effects. This could be related to a theory called: the 'entourage effect', which suggests that different cannabinoids and other compounds act in synergy to amplify each other's effects. However, further research is needed to clarify this.

• According to the Italian researchers, research into the anti-inflammatory, antioxidant and anti-epileptic properties of CBDP will continue.

• Users report relaxing and anxiolytic effects, suggesting that CBDP could have similar uses to CBD in promoting mental well-being.

• Some users who have tried CBDP in combination with CBN have reported on the Reddit discussion forum that they felt significant relaxation, drowsiness, and deeper sleep. This suggests that CBDP may promote relaxation as well as CBD, but this is not yet confirmed by any studies.

• In the experience of users, CBDP has no psychoactive effects.

 

Side effects

There are also currently no scientific studies on what the side effects of CBDP are.

Side effects are CBD rare with and occur mainly at high doses. It is thought that CBDP could have a similar safety profile, but without research this cannot be stated with certainty.

Potential side effects of CBDP:

• Drowsiness and fatigue
• Changes in appetite
• Dry mouth
• Digestive disorders, such as diarrhoea

These side effects tend to be mild and transient, and their intensity can vary depending on several factors, including:

• Dosage and frequency of use
• Body weight and metabolism
• Age and individual sensitivity
• Method of use (vaping, oils, capsules, etc.)

CBDP products

Currently, CBDP products are most commonly sold in the form of vapes and cartridges, vaping liquids, flowers, prerolls and hashes.

Hemnia premium CBDP and CBN vape and Deep cartridge

CBDP and CBN Vape and cartridge called Deep Relaxation combines CBDP and CBN distillate, natural terpenes, kava kava, valerian and lemon balm. The CBDP content is 5% and the CBN content is 90%.

• CBN (cannabinol): a natural cannabinoid found in cannabis that is produced by the aging and oxidation of THC. Its main effects include promoting sleep, relaxation or relieving pain symptoms.
• Kava kava (Piper methysticum): a tropical plant that can help with anxiety, relieve tension and stress, and promote mental well-being.
• Valerian (Valeriana officinalis): one of the best known herbs used to relieve stress, anxiety and insomnia.
• Lemon balm (Melissa officinalis): a natural sedative that helps relieve stress, tension, anxiety and improve sleep.

 

 

When vaping, the substances are absorbed more quickly than, for example, gummies, and the effect is almost immediate (5 to 10 minutes).

With a unique combination of CBDP, CBN, kava kava, valerian and lemon balm, the Deep Relaxation Vape Pen offers support for stress, tension and sleep problems 😴. The device is rechargeable via USB-C and includes a 1ml cartridge. Generally, 1 ml of liquid in the vaping device lasts for approximately 200 to 300 puffs (depending on the size of the puffs and frequency of use).

The Deep Relaxation cartridge connects to a vaporizer or vaping battery with a 510 thread.

Conclusion

The phytocannabinoid CBDP occurs naturally in cannabis, but only in trace amounts. For this reason, it is practically obtained from CBD isolate by a chemical reaction called isomerisation, and is therefore classified as a semi-synthetic cannabinoid.

Although research into its effects is still at an early stage, early findings suggest that it could have relaxing, anti-inflammatory and neuroprotective properties. CBDP is not psychoactive.

Users who have tried a combination of CBDP and CBN have reported deeper sleep, relaxation and stress relief.

As CBDP research is still ongoing, its therapeutic potential is yet to be discovered.

If you're looking for new ways to boost your mental well-being and relaxation, try Deep Relaxation - Premium CBDP and CBN Vape pen, Kava, Valerian, Lemon Balm or Deep Relaxation cartridges 🧘.

  

Author: Patricie Mikolášová

 

Foto: AI

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